IRAK4-IN-6
Product Specifications
CAS Number
2454244-02-9
Target
IRAK, Others
Related Pathways
Immunology/Inflammation, NF-κB, Others
Bioactivity
IRAK4-IN-6 is a selective and orally efficacious inhibitor of IRAK4, demonstrating an IC50 value of 4 nM. This compound specifically targets MyD88 L265P mutant diffuse large B-cell lymphoma [1].
Smiles
COC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1nc(Nc2cnn(C)c2)nc2ccc(CC#N)nc12
Molecular Formula
C25H32N10O2
Molecular Weight
504.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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