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IRAK4-IN-6

Product Specifications

CAS Number

2454244-02-9

Target

IRAK, Others

Related Pathways

Immunology/Inflammation, NF-κB, Others

Bioactivity

IRAK4-IN-6 is a selective and orally efficacious inhibitor of IRAK4, demonstrating an IC50 value of 4 nM. This compound specifically targets MyD88 L265P mutant diffuse large B-cell lymphoma [1].

Smiles

COC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1nc(Nc2cnn(C)c2)nc2ccc(CC#N)nc12

Molecular Formula

C25H32N10O2

Molecular Weight

504.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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