Indirubin-5-sulfonate
Product Specifications
CAS Number
244021-67-8
Target
GSK-3|||Others|||CDK
Related Pathways
Stem Cells|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Others
Bioactivity
Indirubin-5-sulfonate shows inhibitory activity against GSK-3?. Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively.
Smiles
O=C1C(C=2C(N1)=CC=C(S(=O)(=O)O)C2)=C3C(=O)C=4C(N3)=CC=CC4
Molecular Formula
C16H10N2O5S
Molecular Weight
342.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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