INCB 3284 dimesylate
Product Specifications
CAS Number
887401-93-6
Target
Others, CCR
Related Pathways
Others, Immunology/Inflammation, Microbiology/Virology, GPCR/G Protein
Bioactivity
INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM) . It can be used in the research of acute liver failure.
Smiles
CS(=O)(O)=O.O[C@]1(C2=CN=C(OC)C=C2)CC[C@](N3C[C@@H](CC3)NC(CNC(C4=CC(C(F)(F)F)=CC=C4)=O)=O)([H])CC1.CS(=O)(O)=O
Molecular Formula
C28H39F3N4O10S2
Molecular Weight
712.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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