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IDH1 Inhibitor 1

Product Specifications

CAS Number

2234285-81-3

Target

Others, Isocitrate Dehydrogenase (IDH)

Related Pathways

Metabolism, Others

Bioactivity

IDH1 Inhibitor 1 is an orally bioavailable, brain-penetrant, and selective mutant IDH1 inhibitor (IC50s: 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT) .

Smiles

C[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F

Molecular Formula

C20H18F4N6O2

Molecular Weight

450.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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