IDH1 Inhibitor 1
Product Specifications
CAS Number
2234285-81-3
Target
Others, Isocitrate Dehydrogenase (IDH)
Related Pathways
Metabolism, Others
Bioactivity
IDH1 Inhibitor 1 is an orally bioavailable, brain-penetrant, and selective mutant IDH1 inhibitor (IC50s: 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT) .
Smiles
C[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F
Molecular Formula
C20H18F4N6O2
Molecular Weight
450.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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Ethyl [2-Diethylaminothiocarboxyl)]phenylacetate
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