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IDH1 Inhibitor 2

Product Specifications

CAS Number

2244895-42-7

Target

Isocitrate Dehydrogenase (IDH), Dehydrogenase

Related Pathways

Metabolism

Bioactivity

IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor through direct covalent modification of His315, with an IC50 of 110 nM.

Smiles

C[C@H]1[C@]2([C@@](C=3C(CC2)=CN=C(NC4=CC=CC=C4)N3)(C=C(C#N)C1=O)C5=CC=CC=C5)[H]

Molecular Formula

C26H22N4O

Molecular Weight

406.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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