HPN-01
Product Specifications
CAS Number
928655-63-4
Target
IκB/IKK
Related Pathways
NF-κB
Purity
0.9817
Bioactivity
HPN-01 (IKK inhibitor XII) is a selective IKK inhibitor that inhibits IKK-α, IKK-β, and IKK-ε. HPN-01 reduces the severity of the disease, attenuates the immune imbalance, and prolongs the lifespan of mice in a model of autoimmune encephalomyelitis, and can be used to study immune disorders.
Smiles
NC(=O)c1cc(cc(c1N)-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1
Molecular Formula
C19H16ClN3O3S
Molecular Weight
401.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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