HDACs/mTOR Inhibitor 1
Product Specifications
CAS Number
2271413-06-8
Target
MTOR, Apoptosis, HDAC
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDACs/mTOR Inhibitor 1 is a dual HDAC and mammalian target of Rapamycin (mTOR) inhibitor for treating hematologic malignancies, with IC50 values of 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR, and PI3Kα, respectively.
Smiles
C[C@@H]1CN(CCO1)C(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(CCCCCCC(=O)NO)c2n1
Molecular Formula
C28H38N8O5
Molecular Weight
566.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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