Hck-IN-1
Product Specifications
CAS Number
1473404-51-1
Target
Src|||Hck|||HIV Protease
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Proteases/Proteasome|||Microbiology/Virology
Purity
0.9907
Bioactivity
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 ?M and >20 ?M for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for wild-type HIV-1 replication.
Smiles
NC(=S)n1nc(c(\N=N\c2cccc(Cl)c2)c1O)-c1ccc(cc1)[N+]([O-])=O
Molecular Formula
C16H11ClN6O3S
Molecular Weight
402.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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