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H3B-6545

Product Specifications

CAS Number

2052130-80-8

Target

Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Related Pathways

Endocrinology/Hormones

Bioactivity

H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that is orally available. As a novel class of ERα antagonists, H3B-6545 is used in the study of metastatic breast cancers, such as estrogen receptor-positive (ER), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.

Smiles

C(=C(\CC(F)(F)F)/C1=CC=CC=C1)(\C=2C=C3C(=CC2)NN=C3F)/C=4C=CC(OCCNC/C=C/C(N(C)C)=O)=NC4

Molecular Formula

C30H29F4N5O2

Molecular Weight

567.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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