H3B-6545
Product Specifications
CAS Number
2052130-80-8
Target
Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that is orally available. As a novel class of ERα antagonists, H3B-6545 is used in the study of metastatic breast cancers, such as estrogen receptor-positive (ER), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.
Smiles
C(=C(\CC(F)(F)F)/C1=CC=CC=C1)(\C=2C=C3C(=CC2)NN=C3F)/C=4C=CC(OCCNC/C=C/C(N(C)C)=O)=NC4
Molecular Formula
C30H29F4N5O2
Molecular Weight
567.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1647502 1.0 µg DNA
PIGK sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details orb3183444 100 µL
Mitoferrin 2/SLC25A28 Rabbit pAb, Pacific Blue conjugated
Sign In for Pricing
View Details 
