H3B-6545
Product Specifications
CAS Number
2052130-80-8
Target
Estrogen Receptor/ERR|||Estrogen/progestogen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
H3B-6545 is a selective estrogen receptor covalent antagonist (SERCA) that is orally available. As a novel class of ER? antagonists, H3B-6545 is used in the study of metastatic breast cancers, such as estrogen receptor-positive (ER), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.
Smiles
C(=C(\CC(F)(F)F)/C1=CC=CC=C1)(\C=2C=C3C(=CC2)NN=C3F)/C=4C=CC(OCCNC/C=C/C(N(C)C)=O)=NC4
Molecular Formula
C30H29F4N5O2
Molecular Weight
567.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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