GZD856
Product Specifications
CAS Number
1257628-64-0
Target
Apoptosis, PDGFR, Bcr-Abl
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling
Bioactivity
GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.
Smiles
C(C1=C(C(F)(F)F)C=C(NC(=O)C2=CC(C#CC3=CN4C(N=C3)=CC=N4)=C(C)C=C2)C=C1)N5CCN(C)CC5
Molecular Formula
C29H27F3N6O
Molecular Weight
532.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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