GW274150
Product Specifications
CAS Number
210354-22-6
Target
NOS, NO Synthase
Related Pathways
Immunology/Inflammation
Purity
>99.99%
Bioactivity
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS) .GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.
Smiles
C([C@@H](C(O)=O)N)CSCCNC(C)=N
Molecular Formula
C8H17N3O2S
Molecular Weight
219.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1335967 Inquire
Recombinant Shigella boydii serotype 4 HTH-type transcriptional regulator malT (malT), partial
Sign In for Pricing
View Details 
ARP43389_P050-Biotin 100 µL
RSPRY1 Antibody - N-terminal region : Biotin (ARP43389_P050-Biotin)
Sign In for Pricing
View Details