GW274150
Product Specifications
CAS Number
210354-22-6
Target
NOS|||NO Synthase
Related Pathways
Immunology/Inflammation
Purity
>99.99%
Bioactivity
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS) .GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.
Smiles
C([C@@H](C(O)=O)N)CSCCNC(C)=N
Molecular Formula
C8H17N3O2S
Molecular Weight
219.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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