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GW274150 phosphate

Product Specifications

CAS Number

438542-15-5

Target

NO Synthase|||NOS

Related Pathways

Immunology/Inflammation

Purity

0.9802

Bioactivity

GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 ?M in J774 cells. It mitigates experimental renal ischaemia-reperfusion injury and exhibits analgesic effects in rat models of inflammatory and neuropathic pain.

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P(=O)(O)(O)O.C([C@@H](C(O)=O)N)CSCCNC(C)=N

Molecular Formula

C8H20N3O6PS

Molecular Weight

317.3

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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