GW274150 phosphate
Product Specifications
CAS Number
438542-15-5
Target
NO Synthase|||NOS
Related Pathways
Immunology/Inflammation
Purity
0.9802
Bioactivity
GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 ?M in J774 cells. It mitigates experimental renal ischaemia-reperfusion injury and exhibits analgesic effects in rat models of inflammatory and neuropathic pain.
Smiles
P(=O)(O)(O)O.C([C@@H](C(O)=O)N)CSCCNC(C)=N
Molecular Formula
C8H20N3O6PS
Molecular Weight
317.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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