GSK840

Product Specifications

CAS Number

2361146-30-5

Target

RIP kinase

Related Pathways

NF-?B|||Apoptosis

Purity

0.997

Bioactivity

GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor that binds to the RIP3 kinase domain (IC50: 0.9 nM) and inhibits kinase activity (IC50: 0.3 nM) .

Smiles

CNC(=O)c1ccc2n(cnc2c1)-c1ccc(CC(=O)OC(C)(C)C)cc1

Molecular Formula

C21H23N3O3

Molecular Weight

365.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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