GSK2945 hydrochloride (1438071-12-5 free base)
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
GSK2945 hydrochloride is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM) . It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
Smiles
[H]Cl.O=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-]
Molecular Formula
C20H19Cl3N2O2S
Molecular Weight
457.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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