GSK2945
Product Specifications
CAS Number
1438071-12-5
Target
Cytochromes P450, Others
Related Pathways
Others, Metabolism
Bioactivity
GSK2945 is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM) . It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
Smiles
N(CC=1SC(N(=O)=O)=CC1)(CC2=C(C)C=C(Cl)C=C2)CC3=CC=C(Cl)C=C3
Molecular Formula
C20H18Cl2N2O2S
Molecular Weight
421.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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