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GSK2945

Product Specifications

CAS Number

1438071-12-5

Target

Cytochromes P450|||Others

Related Pathways

Others|||Metabolism

Bioactivity

GSK2945 is a highly specific Rev-erb?/REV-ERB? (mouse/human reverse erythroblastosis virus ?) antagonist (EC50s: 21.5 ?M and 20.8 ?M) . It enhances cholesterol 7?-hydroxylase (CYP7A1) level and cholesterol metabolism.

Smiles

N(CC=1SC(N(=O)=O)=CC1)(CC2=C(C)C=C(Cl)C=C2)CC3=CC=C(Cl)C=C3

Molecular Formula

C20H18Cl2N2O2S

Molecular Weight

421.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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