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GSK2850163

Product Specifications

CAS Number

2121989-91-9

Target

IRE1

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9904

Bioactivity

GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α), effectively inhibiting both its RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM) .

Smiles

Cc1ccc(CNC(=O)N2CCC[C@]3(CCN(Cc4ccc(Cl)c(Cl)c4)C3)C2)cc1

Molecular Formula

C24H29Cl2N3O

Molecular Weight

446.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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