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Fiboflapon sodium

Product Specifications

CAS Number

1196070-26-4

Target

FLAP|||LTR|||Leukotriene Receptor

Related Pathways

Immunology/Inflammation|||GPCR/G Protein

Bioactivity

Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.

Smiles

[Na].CCOc1ccc(cn1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c3cc(OCc4ccc(C)cn4)ccc23)cc1

Molecular Formula

C38H43N3NaO4S

Molecular Weight

660.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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