GSK2245035
Product Specifications
CAS Number
1207629-49-9
Target
Others, TNF, IFNAR, TLR
Related Pathways
Apoptosis, Immunology/Inflammation, Others
Bioactivity
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN) -stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα) . It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures.
Smiles
CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1
Molecular Formula
C20H34N6O2
Molecular Weight
390.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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