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GSK2245035

Product Specifications

CAS Number

1207629-49-9

Target

Others, TNF, IFNAR, TLR

Related Pathways

Apoptosis, Immunology/Inflammation, Others

Bioactivity

GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN) -stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα) . It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures.

Smiles

CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1

Molecular Formula

C20H34N6O2

Molecular Weight

390.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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