GNF362
Product Specifications
CAS Number
1003019-41-7
Target
Phosphatase
Related Pathways
Metabolism
Purity
0.9963
Bioactivity
GNF362 is an orally available, selective and potent inhibitor of inositol trisphosphate 3'kinase B (ITPKB), inhibits Itpka and Itpkc, overcomes TMZ chemoresistance, and selectively deletes donor allogeneic reactive T-cells.GNF362 reverses the migratory stimulatory effects of ITPKA overexpression.
Smiles
C[C@@H]1CN(Cc2cn[nH]c2-c2ccc(cc2)C#N)CCN1c1ccc(cn1)C(F)(F)F
Molecular Formula
C22H21F3N6
Molecular Weight
426.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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