GLP-26
Product Specifications
CAS Number
2133017-36-2
Target
HBV
Related Pathways
Microbiology/Virology
Purity
0.9862
Bioactivity
GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.
Smiles
Cc1c(C(=O)C(=O)NCC#C)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1
Molecular Formula
C19H17F2N3O3
Molecular Weight
373.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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