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GKI-1

Product Specifications

CAS Number

2444764-03-6

Target

ROCK, Others

Related Pathways

Stem Cells, Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling

Purity

0.9996

Bioactivity

GKI-1 is a Greatwall (GWL) kinase inhibitor with an IC50 of 4.9 for hGWLFL and 2.5 μM for hGWL-KinDom. It exhibits stronger inhibition on ROCK1 with an IC50 of 11 μM and only weakly inhibits PKA.

Smiles

N(C=1C=C(C=CC1)C=2C=NNC2)C3=CC=C(Cl)C=C3

Molecular Formula

C15H12ClN3

Molecular Weight

269.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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