GKI-1
Product Specifications
CAS Number
2444764-03-6
Target
ROCK, Others
Related Pathways
Stem Cells, Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Purity
0.9996
Bioactivity
GKI-1 is a Greatwall (GWL) kinase inhibitor with an IC50 of 4.9 for hGWLFL and 2.5 μM for hGWL-KinDom. It exhibits stronger inhibition on ROCK1 with an IC50 of 11 μM and only weakly inhibits PKA.
Smiles
N(C=1C=C(C=CC1)C=2C=NNC2)C3=CC=C(Cl)C=C3
Molecular Formula
C15H12ClN3
Molecular Weight
269.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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