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Giredestrant

Product Specifications

CAS Number

1953133-47-5

Target

Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Related Pathways

Endocrinology/Hormones

Purity

0.9956

Bioactivity

Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.

Smiles

C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F

Molecular Formula

C27H31F5N4O

Molecular Weight

522.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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