Giredestrant
Product Specifications
CAS Number
1953133-47-5
Target
Estrogen Receptor/ERR|||Estrogen/progestogen Receptor
Related Pathways
Endocrinology/Hormones
Purity
0.9956
Bioactivity
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand, is an orally active and selective estrogen receptor (ER) antagonist.
Smiles
C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cc(NC2CN(CCCF)C2)cc1F
Molecular Formula
C27H31F5N4O
Molecular Weight
522.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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