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Genz-123346

Product Specifications

CAS Number

943344-58-9

Target

Others, Transferase

Related Pathways

Metabolism, Others

Bioactivity

Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC50 value of 14 nM. Genz-123346 is a potent, orally available glucosylceramide synthase inhibitor.

Smiles

OC([C@H](O)[C@@H](O)C(O)=O)=O.CCCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O.CCCCCCCCC(N[C@H](CN4CCCC4)[C@@H](C5=CC=C(OCCO6)C6=C5)O)=O

Molecular Formula

C52H82N4O14

Molecular Weight

987.23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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