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GDC-0834

Product Specifications

CAS Number

1133432-49-1

Target

BTK

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

GDC-0834 is a potent and selective BTK inhibit that inhibits BTK with an in vitro IC50 of 5.9 nM (biochemical assays) and 6.4 nM (cellular assays), and with an in vivo IC50 of 1.1 μM (mouse) and 5.6 μM (rat) .

Smiles

CN1CCN(C)C(=O)[C@H]1c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(NC(=O)c3cc4CCCCc4s3)c2C)cc1

Molecular Formula

C33H36N6O3S

Molecular Weight

596.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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