GDC-0834
Product Specifications
CAS Number
1133432-49-1
Target
BTK
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
GDC-0834 is a potent and selective BTK inhibit that inhibits BTK with an in vitro IC50 of 5.9 nM (biochemical assays) and 6.4 nM (cellular assays), and with an in vivo IC50 of 1.1 ?M (mouse) and 5.6 ?M (rat) .
Smiles
CN1CCN(C)C(=O)[C@H]1c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(NC(=O)c3cc4CCCCc4s3)c2C)cc1
Molecular Formula
C33H36N6O3S
Molecular Weight
596.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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