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GATA4-NKX2-5-IN-1

Product Specifications

CAS Number

544681-96-1

Target

Others, IKZF

Related Pathways

Immunology/Inflammation, Others

Purity

0.99

Bioactivity

GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.GATA4-NKX2-5-IN-1 dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM.

Smiles

C(NC1=CC=C(N(CC)CC)C=C1)(=O)C=2C(=NOC2C)C3=CC=CC=C3

Molecular Formula

C21H23N3O2

Molecular Weight

349.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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