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Garcinol

Product Specifications

CAS Number

78824-30-3

Target

AChR, Cholinesterase (ChE), Apoptosis, Endogenous Metabolite, Histone Acetyltransferase

Related Pathways

Chromatin/Epigenetic, Metabolism, Apoptosis, Neuroscience

Purity

0.9859

Bioactivity

Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM) . Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.

Smiles

CC(C)=CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C

Molecular Formula

C38H50O6

Molecular Weight

602.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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