Garcinol
Product Specifications
CAS Number
78824-30-3
Target
AChR|||Cholinesterase (ChE) |||Apoptosis|||Endogenous Metabolite|||Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic|||Metabolism|||Apoptosis|||Neuroscience
Purity
0.9859
Bioactivity
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 ?M) and p300/CPB-associated factor (PCAF, IC50 = 5 ?M) . Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 ?M and 7.39 ?M, respectively.
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CC(C)=CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C
Molecular Formula
C38H50O6
Molecular Weight
602.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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