γ-Secretase modulator 4

1420200-82-3

Others, Gamma-secretase

Stem Cells, Proteases/Proteasome, Others, Neuroscience

γ-Secretase modulator 4 is a potent γ-secretase modulator that reduces Aβ42 levels with IC50s of 0.017 μM in mice and 0.014 μM in humans.

CC1=C([C@H]2C=3N(C=C(N3)C4=CC=5C(N4)=CC=C(C#N)C5OC)CCO2)C=CC=C1F

C23H19FN4O2

402.42

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