γ-Secretase modulator 4

1420200-82-3

Others|||Gamma-secretase

Stem Cells|||Proteases/Proteasome|||Others|||Neuroscience

?-Secretase modulator 4 is a potent ?-secretase modulator that reduces A?42 levels with IC50s of 0.017 ?M in mice and 0.014 ?M in humans.

CC1=C([C@H]2C=3N(C=C(N3)C4=CC=5C(N4)=CC=C(C#N)C5OC)CCO2)C=CC=C1F

C23H19FN4O2

402.42

Cool pack

-20°C

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