FR 167653 free base
Product Specifications
CAS Number
158876-65-4
Target
Others, Autophagy, p38 MAPK
Related Pathways
Autophagy, Others, MAPK
Bioactivity
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.
Smiles
C(C(=O)C1=CC=CC=C1)(=O)N2NC3=C(C(=NN3CC2)C4=CC=C(F)C=C4)C=5C=CN=CC5
Molecular Formula
C24H18FN5O2
Molecular Weight
427.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Monoclonal Histone H2AX [p Ser139] Antibody (2207D) [Alexa Fluor 594]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
FAB2288T 0.1 mL
Rabbit Monoclonal Histone H2AX [p Ser139] Antibody (2207D) [Alexa Fluor 594]
Sign In for Pricing
View Details bs-14407R-APC-Cy7 100 µL
DOLPP1 Polyclonal Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details ![Mouse Monoclonal CD40 Ligand/TNFSF5 Antibody (TRAP1.3.6) [DyLight 488]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP1-42527G 0.1 mL
Mouse Monoclonal CD40 Ligand/TNFSF5 Antibody (TRAP1.3.6) [DyLight 488]
Sign In for Pricing
View Details 
120501Q1-AAT 100 Tests
PE/iFluor® 647 Anti-human CD205 Antibody *HD30*
Sign In for Pricing
View Details