FR 167653 free base
Product Specifications
CAS Number
158876-65-4
Target
Others|||Autophagy|||p38 MAPK
Related Pathways
Autophagy|||Others|||MAPK
Bioactivity
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-? and IL-1? production via specific inhibition of p38 MAPK activity.
Smiles
C(C(=O)C1=CC=CC=C1)(=O)N2NC3=C(C(=NN3CC2)C4=CC=C(F)C=C4)C=5C=CN=CC5
Molecular Formula
C24H18FN5O2
Molecular Weight
427.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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