FM26
Product Specifications
CAS Number
2407981-35-3
Target
ROR
Related Pathways
Metabolism
Bioactivity
FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM.
Smiles
C(NC1=CC=C(C(O)=O)C=C1)C=2C(=NOC2C=3C=CNC3)C4=C(C(F)(F)F)C=CC=C4Cl
Molecular Formula
C22H15ClF3N3O3
Molecular Weight
461.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
66820126 3x 1.0µg DNA
RGD1310358 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details 
SIPC602Hu01-01 10 µg
Recombinant HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Sign In for Pricing
View Details SIPC602Hu01-02 50 µg
Recombinant HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Sign In for Pricing
View Details SIPC602Hu01-03 200 µg
Recombinant HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Sign In for Pricing
View Details SIPC602Hu01-04 1 mg
Recombinant HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Sign In for Pricing
View Details SIPC602Hu01-05 5 mg
Recombinant HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Sign In for Pricing
View Details