FG 7142
Product Specifications
CAS Number
78538-74-6
Target
GABA Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
0.9881
Bioactivity
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM) . FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM) .
Smiles
CNC(=O)c1cc2c(cn1)[nH]c1ccccc21
Molecular Formula
C13H11N3O
Molecular Weight
225.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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