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(+) -Shikonin

Product Specifications

CAS Number

517-89-5

Target

PKM, HIV Protease, NF-κB, Chloride channel, AIM2, TNF

Related Pathways

Apoptosis, Metabolism, Membrane transporter/Ion channel, Immunology/Inflammation, NF-κB, Proteases/Proteasome, Microbiology/Virology

Purity

0.999

Bioactivity

(+) -Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. (+) - Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.

Smiles

CC(C)=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

Molecular Formula

C16H16O5

Molecular Weight

288.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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