Dxd
Product Specifications
CAS Number
1599440-33-1
Target
ADC Cytotoxin, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Purity
>99.99%
Bioactivity
Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM) . Dxd was used as a conjugate drug for HER2-targeted ADCs.
Smiles
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)CO)c(c3Cn1c2=O)c45
Molecular Formula
C26H24FN3O6
Molecular Weight
493.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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