Exatecan

Product Specifications

CAS Number

171335-80-1

Target

ADC Cytotoxin|||Topoisomerase

Related Pathways

Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

Purity

0.9996

Bioactivity

Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL) .Exatecan has antitumor activity and may be used in cancer research.

Smiles

N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

Molecular Formula

C24H22FN3O4

Molecular Weight

435.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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