Exatecan
Product Specifications
CAS Number
171335-80-1
Target
ADC Cytotoxin|||Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair
Purity
0.9996
Bioactivity
Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL) .Exatecan has antitumor activity and may be used in cancer research.
Smiles
N[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C24H22FN3O4
Molecular Weight
435.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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