ESI-08
Product Specifications
CAS Number
301177-43-5
Target
CAMP, Ras
Related Pathways
MAPK, GPCR/G Protein
Purity
0.9905
Bioactivity
ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.
Smiles
Cc1ccc(C)c(CSc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)c1
Molecular Formula
C20H23N3OS
Molecular Weight
353.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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