Epertinib
Product Specifications
CAS Number
908305-13-5
Target
EGFR|||HER
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM) . It displays a strong antitumor activity.
Smiles
N(C=1C2=C(C=CC(\C(=N\OC[C@H]3COCCN3)\C#CC)=C2)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4
Molecular Formula
C30H27ClFN5O3
Molecular Weight
560.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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