Epertinib

Product Specifications

CAS Number

908305-13-5

Target

EGFR|||HER

Related Pathways

JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM) . It displays a strong antitumor activity.

Smiles

N(C=1C2=C(C=CC(\C(=N\OC[C@H]3COCCN3)\C#CC)=C2)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4

Molecular Formula

C30H27ClFN5O3

Molecular Weight

560.02

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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